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Skin Science

32.9% Wrinkle Reduction in 8 Weeks: Inside the Clinical Trials

 ·  Sonal Chavda-Sitaram ·  5 min read
32.9% Wrinkle Reduction in 8 Weeks: Inside the Clinical Trials

Most collagen supplements make claims without clinical validation. Complete Dual Collagen Complex has published, peer-reviewed evidence from independent trials conducted by a university pharmacy department. The results are remarkable: 32.9% wrinkle reduction in eight weeks. But the depth of evidence goes far beyond that single statistic.

The gold standard: double-blind, randomised, placebo-controlled

Chia Nan University of Pharmacy & Science conducted an independent trial following pharmaceutical-grade protocols. This wasn't an in-house study or marketing-driven research. It was an Institutional Review Board (IRB) approved clinical trial with rigorous methodology.

The trial design followed the gold standard:

  • Double-blind: Neither participants nor researchers knew who received VeCollal® versus placebo
  • Randomised: Participants were randomly assigned to treatment or control groups
  • Placebo-controlled: Results were compared against an inactive control group
  • 90 participants: Sufficient sample size for statistical significance

Participants consumed 5g of Complete Dual Collagen Complex daily for eight weeks. Comprehensive measurements were taken at baseline, week four, and week eight.


Multiple parameters, comprehensive results

The trial didn't just measure wrinkles. Six distinct skin parameters were assessed using validated measurement techniques:

Wrinkles: 32.9% reduction

Using validated skin imaging technology, researchers measured wrinkle depth and volume. After eight weeks, the average wrinkle value decreased by 32.9%. This reduction is comparable to or exceeds the best animal collagen supplements on the market, achieved with a modest 5g daily dose.

Collagen density: 7.7% increase

Perhaps more significant than wrinkle reduction is the increase in actual collagen density. After eight weeks, collagen density values measured 7.7% higher than baseline. This demonstrates that Complete Dual Collagen Complex doesn't just improve surface appearance but increases the structural protein that determines skin firmness and elasticity.

Elasticity: 6% improvement

Skin elasticity (the ability to return to original shape after stretching) improved by 6%. Loss of elasticity causes sagging and contributes to visible ageing. Improved elasticity means firmer, more resilient skin.

Texture: 13.1% improvement

Skin roughness decreased by 13.1%. Smoother texture creates the appearance of healthier, more youthful skin. This parameter reflects how your skin actually feels, not just how it looks.

Hydration: 6% increase

Skin hydration levels increased by 6%. Adequate hydration is essential for maintaining plumpness, reducing the appearance of fine lines, and supporting barrier function.

Pore size: 5.6% reduction

Visible pores decreased by 5.6%. Whilst genetics largely determine pore size, improved skin structure and collagen density can minimise pore appearance.

Safety validated

Beyond efficacy measurements, the trial included comprehensive safety evaluation. Liver and kidney function markers were assessed at baseline and week eight. No significant changes were detected, confirming Complete Dual Collagen Complex is safe for daily use.

This level of safety monitoring mirrors pharmaceutical standards, ensuring therapeutic products meet rigorous evidence and safety requirements.

Three factors explain the efficacy:

Human-identical amino acid profile: VeCollal® matches human Type I collagen exactly. Your body receives the precise ratios it needs for efficient collagen synthesis, with no missing essential amino acids.

Superior bioavailability: Absorption studies demonstrate VeCollal® amino acids become immediately available in the digestive system, whilst animal collagen requires extensive breakdown. More amino acids reach your cells over the same timeframe.

Gene expression activation: Asiaticoside, ginsenosides, and vitamin C don't just provide building blocks; they signal your cells to increase collagen gene expression. This dual approach (supply plus activation) drives the 134.97% increase in collagen production observed in fibroblast studies.


Published in peer-reviewed literature

The trial results weren't just presented at a conference or published in a company white paper. They appeared in the Journal of Functional Foods, a respected peer-reviewed publication in nutraceutical research.

The trial results weren't just presented at a conference or published in a company white paper. They appeared in the

Peer review means independent scientists evaluated the methodology, statistical analysis, and conclusions before publication. This scrutiny ensures the results meet academic standards for scientific rigour.

The published paper is publicly accessible, allowing consumers, healthcare professionals, and researchers to examine the complete data, not just marketing highlights.


Beyond skin: joint health outcomes

Complete Dual Collagen Complex includes both Type I (for skin) and Type II (for joints). Its the ONLY collagen support on the market offering both. Separate trials on VeCollal® Type II demonstrated significant joint health improvements in 12 weeks:

  • 44% reduction in joint discomfort
  • 67% reduction in joint stiffness
  • 61% improvement in physical function

Additionally, VeCollal® Type II activates up to 50% of the Type II collagen gene in cartilage cells, stimulates osteoblast activity for bone regeneration, and promotes your body's own secretion of chondroitin and hyaluronic acid for joint lubrication.


The Complete by Dr SCS difference

The Radiance system delivers 10g of combined VeCollal® Type I and Type II daily because that's the dose supported by evidence. Its > 4x the dose of others.

Every ingredient, every ratio, every claim reflects published research and clinical trials. This is pharmaceutical-grade formulation applied to skincare.

What to expect

Based on the clinical trial timeline:

  • Week 4: Early improvements in hydration and texture
  • Week 8: Measurable wrinkle reduction, collagen density increase, improved elasticity
  • Week 12: Continued improvement, optimal joint health benefits
  • Week 12+: Sustained results with continued supplementation

Individual results vary based on age, skin condition, lifestyle factors, and genetics. However, the clinical trial demonstrates that average improvements are substantial and statistically significant.

The evidence is clear

Complete Dual Collagen Complex isn't marketed on aspirational claims or influencer testimonials. It's validated by independent, peer-reviewed clinical trials conducted by a university pharmacy department.

32.9% wrinkle reduction. 7.7% collagen density increase. Six measurable skin parameters improved. Safety confirmed. Published in scientific literature.

This is what evidence-based skincare looks like.

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<p class="ql-block" data-block-id="block-7c8cdb1e-f132-4e3f-8843-4a9dfcb65cba"><strong>The mechanism behind the results</strong></p> <p class="ql-block" data-block-id="block-09c2d377-6f12-4a81-9814-cd709f81f6e2">Why does Complete Dual Collagen Complex produce these results whilst many collagen supplements show minimal effects?</p>

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Written by
Sonal Chavda-Sitaram

Founder of Complete by Dr SCS. MRPharmS, PhD — writing on evidence-based skin health.

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